Absolute quantitative detection of ABL tyrosine kinase domain point mutations in chronic myeloid leukemia using a novel nanofluidic platform and mutation-specific PCR.

Oehler, VG and Qin, J and Ramakrishnan, R and Facer, G and Ananthnarayan, S and Cummings, C and Deininger, M and Shah, N and McCormick, F and Willis, S and Daridon, A and Unger, M and Radich, J (2008) Absolute quantitative detection of ABL tyrosine kinase domain point mutations in chronic myeloid leukemia using a novel nanofluidic platform and mutation-specific PCR. Leukemia : official journal of the Leukemia Society of America, Leukemia Research Fund, U.K. ISSN 1476-5551

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Abstract

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Item Type:	Article or Abstract
Additional Information:	This article is available to subscribers only via the Article URL given above.
DOI:	10.1038/leu.2008.183
PubMed ID:	18615105
NIHMSID:	NIHMS82770
Grant Numbers:	K23 CA106796-04, P01 CA18029-33
Keywords or MeSH Headings:	Fusion Proteins, bcr-abl/genetics* Humans Leukemia, Myelogenous, Chronic, BCR-ABL Positive/diagnosis* Leukemia, Myelogenous, Chronic, BCR-ABL Positive/genetics* Microfluidic Analytical Techniques/instrumentation Nanotechnology/instrumentation* Point Mutation* Polymerase Chain Reaction/methods* Polymerase Chain Reaction/standards Sensitivity and Specificity
Subjects:	Cellular and Organismal Processes > Genetic processes > Mutation Diseases > Hematologic and lymphatic diseases > Leukemia Research Methodologies
Depositing User:	Library Staff
Date Deposited:	11 Dec 2008 21:46
Last Modified:	14 Feb 2012 14:42
URI:	http://authors.fhcrc.org/id/eprint/197

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