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Infectious agents and colorectal cancer: a review of Helicobacter pylori, Streptococcus bovis, JC virus, and human papillomavirus.

Burnett-Hartman, Andrea N and Newcomb, Polly A and Potter, John D (2008) Infectious agents and colorectal cancer: a review of Helicobacter pylori, Streptococcus bovis, JC virus, and human papillomavirus. Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology, 17 (11). pp. 2970-2979. ISSN 1055-9965

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Article URL: http://cebp.aacrjournals.org/cgi/reprint/17/11/297...

Abstract

Based on the high volume of bacteria and viruses that the intestine is exposed to and the importance of infectious agents in some gastrointestinal and anogenital cancers, it is not surprising the many studies have evaluated the association between colorectal cancer and infectious agents. This review highlights investigations of four agents in relation to colorectal cancer. Helicobacter pylori, Streptococcus bovis, JC virus, and human papillomavirus have all been evaluated as possible etiologic agents for colorectal cancer. For each of these agents, a review of possible mechanisms for carcinogenesis and epidemiologic evidence is discussed, and future directions for research are proposed.

Item Type: Article
Additional Information: This article is available to subscribers only via the URL above for the first 12 months following publication.
DOI: 10.1158/1055-9965.EPI-08-0571
PubMed ID: 18990738
NIHMSID: NIHMS105366
PMCID: PMC2676114
Grant Numbers: T32 CA009168-32
Keywords or MeSH Headings: Colorectal Neoplasms/microbiology/virology; Helicobacter pylori/pathogenicity; Humans; JC Virus/pathogenicity; Papillomaviridae/pathogenicity; Streptococcus bovis/pathogenicity;
Subjects: Diseases > Solid tumors > Digestive system cancer
Organisms > Bacteria
Organisms > Viruses
Depositing User: Library Staff
Date Deposited: 25 Mar 2009 20:58
Last Modified: 14 Feb 2012 14:42
URI: http://authors.fhcrc.org/id/eprint/263

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