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Gene expression changes in normal haematopoietic cells.

Lionberger, Jack M and Stirewalt, Derek L (2009) Gene expression changes in normal haematopoietic cells. Best practice & research. Clinical haematology, 22 (2). pp. 249-269. ISSN 1532-1924

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Article URL: http://www.bprch.com/article/S1521-6926%2809%29000...

Abstract

The complexity of the healthy haematopoietic system is immense, and as such, one must understand the biology driving normal haematopoietic expression profiles when designing experiments and interpreting expression data that involve normal cells. This article seeks to present an organised approach to the use and interpretation of gene profiling in normal haematopoiesis and broadly illustrates the challenges of selecting appropriate controls for high-throughput expression studies.

Item Type: Article
Additional Information: This final published version of this article is available to subscribers only via the URL above.
DOI: 10.1016/j.beha.2009.05.005
PubMed ID: 19698932
Keywords or MeSH Headings: * Aging/genetics * Cell Differentiation * Environmental Exposure * Epigenesis, Genetic/physiology * Female * Gene Expression/drug effects * Gene Expression/physiology* * Gene Expression Profiling * Genetic Techniques * Hematopoietic Stem Cells/physiology * Hematopoietic System/cytology* * Hematopoietic System/physiology * Humans * Male * Membrane Proteins/physiology * Oligonucleotide Array Sequence Analysis * Proteome/physiology * Transcription Factors/physiology
Depositing User: Library Staff
Date Deposited: 02 Oct 2009 21:56
Last Modified: 14 Feb 2012 14:42
URI: http://authors.fhcrc.org/id/eprint/340

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