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Is the incidence of invasive vulvar cancer increasing in the United States?

Bodelon, Clara and Madeleine, Margaret M and Voigt, Lynda F and Weiss, Noel S (2009) Is the incidence of invasive vulvar cancer increasing in the United States? Cancer causes & control : CCC, 20 (9). pp. 1779-1782. ISSN 1573-7225

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Article URL: http://dx.doi.org/10.1007/s10552-009-9418-8

Abstract

OBJECTIVE: To document incidence rates of vulvar cancer, specifically invasive vulvar cancer, from 1973 to 2004 in the United States. METHODS: Nine US cancer registries from the Surveillance, Epidemiology, and End Results (SEER) databases were used to identify women aged 15-84 years, who were first diagnosed with vulvar cancer during 1973-2004. Age-adjusted incidence rates and annual percentage changes were calculated for different time periods, stage of the disease, age, race, and geographic area. RESULTS: During 1973-2004, the incidence of in situ vulvar tumors increased by an average of 3.5% per year (95% CI: 2.9%, 4.1%), while the incidence of invasive tumors increased 1.0% per year (95% CI: 0.6%, 1.4%). An increasing incidence was observed for localized and regional invasive tumors. To at least some degree, the rise of incidence rates of incidence tumors was evident in every age category, race, and geographic region. CONCLUSIONS: Incidence rates of invasive vulvar cancer have increased in the United States during the last three decades. The reasons for this increase are unknown.

Item Type: Article
Additional Information: The final publication is available at www.springerlink.com
DOI: 10.1007/s10552-009-9418-8
PubMed ID: 19680749
NIHMSID: NIHMS187598
PMCID: PMC2868506
Grant Numbers: T32 CA009168
Keywords or MeSH Headings: Adolescent; Adult; Age Distribution; Aged; Aged, 80 and over; Female; Humans; Incidence; Middle Aged; SEER Program; United States; Vulvar Neoplasms/epidemiology/pathology; Young Adult;
Subjects: Diseases > Solid tumors
Research Methodologies > Epidemiology
Depositing User: Library Staff
Date Deposited: 13 Mar 2010 00:05
Last Modified: 14 Feb 2012 14:43
URI: http://authors.fhcrc.org/id/eprint/406

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