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Fishing for the secrets of vertebrate evolution in threespine sticklebacks.

Peichel, Catherine L (2005) Fishing for the secrets of vertebrate evolution in threespine sticklebacks. Developmental dynamics : an official publication of the American Association of Anatomists, 234 (4). pp. 815-23. ISSN 1058-8388

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Article URL: http://www3.interscience.wiley.com/journal/1121369...

Abstract

The threespine stickleback (Gasterosteus aculeatus) is rapidly emerging as a new model genetic system to study questions at the interface of evolution and development. The relatively rapid and recent diversification of this small teleost fish, combined with the development of genetic and genomic tools for this fish, provides an unprecedented opportunity to identify the genetic and molecular basis of morphological variation in natural populations of vertebrates. Recently, the genes underlying two different adaptive morphological traits in stickleback have been identified. This work has provided answers to four longstanding questions in the field of evolution and development: (1) How many genes underlie morphological variation in natural populations? (2) What are the genes that underlie morphological variation in natural populations? (3) Do coding or regulatory mutations underlie morphological evolution? (4) What is the molecular and genetic basis of parallel morphological evolution? Because stickleback populations also display natural variation in morphology, life history, physiology, and behavior, extending the approaches used to identify the genetic basis of morphological variation in sticklebacks to other phenotypes is sure to yield further important insights into the genetic and developmental basis of diversity in natural populations.

Item Type: Article
Additional Information: Courtesy of the publisher, this article is available Open Access at the Article URL above.
DOI: 10.1002/dvdy.20564
PubMed ID: 16252286
Grant Numbers: GM71854, 1003370
Keywords or MeSH Headings: Adaptation, Biological/genetics; Animals; Chromosome Mapping/methods; Crosses, Genetic; Evolution; Genes/genetics; Models, Animal; Morphogenesis/genetics; Mutation/genetics; Phenotype; Smegmamorpha/anatomy & histology/embryology/genetics;
Subjects: Research Methodologies > Genomics
Cellular and Organismal Processes > Evolution
Organisms > Model organisms
Cellular and Organismal Processes > Development
Depositing User: Library Staff
Date Deposited: 18 Sep 2008 21:41
Last Modified: 10 May 2010 22:15
URI: http://authors.fhcrc.org/id/eprint/50

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