Linas, B P and Wang, B and Smurzynski, M and Losina, E and Bosch, R J and Schackman, B R and Rong, J and Sax, P E and Walensky, R P and Schouten, J and Freedberg, K A (2011) The impact of HIV/HCV co-infection on health care utilization and disability: results of the ACTG Longitudinal Linked Randomized Trials (ALLRT) Cohort. Journal of viral hepatitis, 18 (7). pp. 506-12. ISSN 1365-2893
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Abstract
HIV/hepatitis C virus (HCV) co-infection places a growing burden on the HIV/AIDS care delivery system. Evidence-based estimates of health services utilization among HIV/HCV co-infected patients can inform efficient planning. We analyzed data from the ACTG Longitudinal Linked Randomized Trials (ALLRT) cohort to estimate resource utilization and disability among HIV/HCV co-infected patients and compare them to rates seen in HIV mono-infected patients. The analysis included HIV-infected subjects enrolled in the ALLRT cohort between 2000 and 2007 who had at least one CD4 count measured and completed at least one resource utilization data collection form (N = 3143). Primary outcomes included the relative risk of hospital nights, emergency department (ED) visits, and disability days for HIV/HCV co-infected vs HIV mono-infected subjects. When controlling for age, sex, race, history of AIDS-defining events, current CD4 count and current HIV RNA, the relative risk of hospitalization, ED visits, and disability days for subjects with HIV/HCV co-infection compared to those with HIV mono-infection were 1.8 (95% CI: 1.3-2.5), 1.7 (95% CI: 1.4-2.1), and 1.6 (95% CI: 1.3-1.9) respectively. Programs serving HIV/HCV co-infected patients can expect approximately 70% higher rates of utilization than expected from a similar cohort of HIV mono-infected patients.
| Item Type: | Article or Abstract |
|---|---|
| PubMed ID: | 20546501 |
| Depositing User: | Library Staff |
| Date Deposited: | 28 Oct 2011 16:47 |
| Last Modified: | 14 Feb 2012 14:44 |
| URI: | http://authors.fhcrc.org/id/eprint/512 |
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