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Selective Targeting of Sirtuin Isoforms for Cancer Therapeutics

Morris, Valerie (2014) Selective Targeting of Sirtuin Isoforms for Cancer Therapeutics. Science Spotlight, 4 (7).

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Additional Information: Mahajan, S.S., Scian, M., Sripathy, S., Posakony, J., Lao, U., Loe, T.K., Leko, V., Thalhofer, A., Schuler, A.D., Bedalov, A., Simon, J.A. 2014. Development of Pyrazolone and Isoxazol-5-one Cambinol Analogues as Sirtuin Inhibitors. Journal of Medicinal Chemistry 57: 3283-94. See also: Heltweg, B., Gatbonton, T., Schuler, A.D., Posakony, J., Li, H., Goehle, S., Kollipara, R., Depinho, R.A., Gu, Y., Simon, J.A., Bedalov, A. 2006. Antitumor activity of a small-molecule inhibitor of human silent information regulator 2 enzymes. Cancer Research 66:4368-4377.
Collections: Science Spotlight
Depositing User: Ben Abraham
Date Deposited: 19 Mar 2015 18:30
Last Modified: 19 Mar 2015 18:30

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