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Enhanced Affinity T-Cell Receptors for Tumor Antigens Are Safe for Gene Therapy

Morris, Valerie (2013) Enhanced Affinity T-Cell Receptors for Tumor Antigens Are Safe for Gene Therapy. Science Spotlight, 3 (7).

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Article URL: http://www.bloodjournal.org/content/122/3/348
Item Type: Article
Additional Information: Schmitt TM, Aggen DH, Stromnes IM, Dossett ML, Richman SA, Kranz DM, Greenberg PD. 2013. Enhanced-affinity murine TCRs for tumor/self-antigens can be safe in gene therapy despite surpassing the threshold for thymic selection. Blood, Epub ahead of print, doi: 10.1182/blood-2013-01-478164. Also see: Chapuis AG, Ragnarsson GB, Nguyen HN, Chaney CN, Pufnock JS, Schmitt TM, Duerkopp N, Roberts IM, Pogosov GL, Ho WY, Ochsenreither S, Wölfl M, Bar M, Radich JP, Yee C, Greenberg PD. 2013. Transferred WT1-reactive CD8+ T cells can mediate antileukemic activity and persist in post-transplant patients. Science Translational Medicine 5:174ra27.
Collections: Science Spotlight
Depositing User: Ben Abraham
Date Deposited: 19 Mar 2015 20:54
Last Modified: 19 Mar 2015 20:54
URI: http://authors.fhcrc.org/id/eprint/773

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