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Souped-Up Cars Drive T-Cell Killing Of ROR1-Positive Tumors

Morris, Valerie (2013) Souped-Up Cars Drive T-Cell Killing Of ROR1-Positive Tumors. Science Spotlight, 3 (6).

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Additional Information: Hudecek M, Lupo Stanghellini MT, Kosasih PL, Sommermeyer D, Jensen M, Rader C, Riddell S. 2013. Receptor affinity and extracellular domain modifications affect tumor recognition by ROR1-specific chimeric antigen receptor T-cells. Clinical Cancer Research. Epub ahead of print, doi: 10.1158/1078-0432.CCR-13-0330 
 Also see: Hudecek M, Schmitt TM, Baskar S, Lupo-Stanghellini MT, Nishida T, Yamamoto TN, Bleakley M, Turtle CJ, Chang WC, Greisman HA, Wood B, Maloney DG, Jensen MC, Rader C, Riddell SR. 2010. The B-cell tumor-associated antigen ROR1 can be targeted with T cells modified to express a ROR1-specific chimeric antigen receptor. Blood 116:4532-41. Turtle CJ, Hudecek M, Jensen MC, Riddell SR. 2012. Engineered T cells for anti-cancer therapy. Current Opinion Immunology 24:633-9
Collections: Science Spotlight
Depositing User: Ben Abraham
Date Deposited: 19 Mar 2015 21:03
Last Modified: 19 Mar 2015 21:03

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