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Respiratory viruses other than influenza virus: impact and therapeutic advances.

Nichols, W Garrett and Peck Campbell, Angela J and Boeckh, Michael (2008) Respiratory viruses other than influenza virus: impact and therapeutic advances. Clinical microbiology reviews, 21 (2). pp. 274-290. ISSN 1098-6618

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Though several antivirals have been developed and marketed to treat influenza virus infections, the development of antiviral agents with clinical activity against other respiratory viruses has been more problematic. Here we review the epidemiology of respiratory viral infections in immunocompetent and immunocompromised hosts, examine the evidence surrounding the currently available antivirals for respiratory viral infections other than influenza, highlight those that are in the pipeline, and discuss the hurdles for development of such agents.

Item Type: Article or Abstract
Additional Information: This article will be available in PubMed Central on 04/01/09.
DOI: 10.1128/CMR.00045-07
PubMed ID: 18400797
PMCID: PMC2292575
Grant Numbers: CA 18029, HL 081585
Keywords or MeSH Headings: Antiviral Agents/pharmacology/therapeutic use; Bronchial Diseases/diagnosis/economics/microbiology/prevention & control/therapy; Community-Acquired Infections/drug therapy/prevention & control; Humans; Respiratory Tract Infections/drug therapy/virology; Virus Diseases/drug therapy;
Subjects: Diseases > Viral diseases
Therapeutics > Drug Therapy
Depositing User: Library Staff
Date Deposited: 27 Oct 2008 21:47
Last Modified: 14 Feb 2012 14:42

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