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Antibodies with Distinct Specificities Neutralize Diverse HIV-1 Variants

Arnegard, Matthew (2012) Antibodies with Distinct Specificities Neutralize Diverse HIV-1 Variants. Science Spotlight, 2 (9).

Antibodies with Distinct Specificities Neutralize Diverse HIV-1 Variants.pdf - Published Version
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Additional Information: Goo L, Jalalian-Lechak Z, Richardson BA, Overbaugh J. 2012. A combination of broadly neutralizing HIV-1 monoclonal antibodies targeting distinct epitopes effectively neutralizes variants found in early infection. J. Virol. Epub ahead of print, doi:10.1128/JVI.01414-12. Also see: Wu X, Parast AB, Richardson BA, Nduati R, John-Stewart G, Mbori-Ngacha D, Rainwater SM, Overbaugh J. 2006. Neutralization escape variants of human immunodeficiency virus type 1 are transmitted from mother to infant. J. Virol. 80:835-44. Klein F, Gaebler C, Mouquet H, Sather DN, Lehmann C, Scheid JF, Kraft Z, Liu Y, Pietzsch J, Hurley A, Poignard P, Feizi T, Morris L, Walker BD, Fätkenheuer G, Seaman MS, Stamatatos L, Nussenzweig MC. 2012. Broad neutralization by a combination of antibodies recognizing the CD4 binding site and a new conformational epitope on the HIV-1 envelope protein. J. Exp. Med. 209:1469-1479.
Collections: Science Spotlight
Depositing User: Ben Abraham
Date Deposited: 20 Mar 2015 22:02
Last Modified: 20 Mar 2015 22:02

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