Colman-Lerner, Alejandro and Brent, Roger (2000) Using peptide aptamers to analyse the proteome. Trends in Cell Biology, 12S. pp. 56-60. ISSN 1471-1931
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Abstract
At the start of the 20th century, the 'rediscovery of Mendel' allowed the consideration of inheritance on a rational, scientific (albeit abstract) basis. During the period 1910-1920, T.H. Morgan and co-workers began to lay the groundwork for the practice of manipulative transmission genetics. This allowed researchers to collect mutants affected in a given genetic process, map those mutations to loci (genes), and further study the effects of combinations of those genes. The eventual linkage of genes to protein products was of course one of the early triumphs of molecular biology. Continuing improvements in transmission genetic methods, and their extension to more and more organisms, arguably accounted for the bulk of the increase in biological understanding during the latter half of the 20th century.
| Item Type: | Article or Abstract |
|---|---|
| Additional Information: | Published in New Technologies for Life Sciences: A Trends Guide, a special issue to celebrate 25 years of Trends publishing |
| Depositing User: | Allysha Eyler |
| Date Deposited: | 06 Oct 2016 15:25 |
| Last Modified: | 06 Oct 2016 17:15 |
| URI: | http://authors.fhcrc.org/id/eprint/1196 |
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